Vegas is first in the Pacific Division with 90 points, three ahead of the Edmonton Oilers.
Patrick Kane had a goal and two assists, and Lucas Raymond and Alex DeBrincat also scored for the Red Wings (32-31-6), who have lost eight of their past 10. Cam Talbot made 30 saves.
“We have to be honest with each other. We were, again tonight, between periods,” Red Wings coach Todd McLellan said. “We talk about wanting to be in the playoffs, but we're not sure we always want to be in shooting lanes. We're not sure we want to do some things, and I'm not saying everybody. Do we really want to do it around the net? Do we really want to get hit by a puck? Do we want to do the board work when it's hard? If the answer is yes to that from everybody, then we have a chance. If the answer is yes to those questions from 85 percent of the players, we don't.”
Detroit remains five points behind the Montreal Canadiens for the second wild card into the Stanley Cup Playoffs from the Eastern Conference.
Raymond scored at 4:47 of the first period to give the Red Wings a 1-0 lead on the power play. His shot from the left circle went off Alex Pietrangelo’s stick and through Hill’s five-hole.