Lee made it 2-0 with a power-play goal at 10:16, redirecting DeAngelo's point shot from the top of the crease.
Lee scored his second power-play goal of the period to extend the lead to 3-0 at 19:06. DeAngelo’s shot from the point hit Lee in front, but the puck dropped down at the left post, where the Islanders captain lifted it in.
The goal came shortly after Rittich stopped Frank Vatrano on a short-handed breakaway.
"Tough coming back from 3-0 in this game," Quenneville said. "We had a decent start to the year, and now we're in a different stretch here. We try to get points every day, every game. Our team game had signs there, but when you get down 3-0, it gets a little bit wide open. We're trying to be so creative that it sometimes could be hazardous."
Leo Carlsson made it 3-1 at 5:34 of the second period during 4-on-4 play. After winning an offensive zone face-off, he beat Rittich glove side with a shot from the left circle.
Terry cut it to 3-2 with a short-handed goal at 2:37 of the third period. Ryan Poehling won a race for the puck with Matthew Schaefer before passing across to Terry, who was all alone in the low slot and made a move before beating Rittich five-hole.
“Yeah, I mean, these games are going to happen," Terry said. "I felt we came out really strong. We could tell we had our legs tonight. ... Things kind of escalated quickly in a short amount of time.”
Holmstrom pushed it to 4-2 at 6:06. He skated around Olen Zellweger on a rush down the left wing, cut across the crease, and tucked a backhand past Husso's left pad.
Ryan Pulock made it 5-2 at 14:46 when his wrist shot from the right boards deflected off the stick of Chris Kreider and over the glove of Husso. It was his first goal of the season.
“We lost Bo. We obviously know how important he is and how much he does for us on the ice every night, and we did a good job of filling that as much as we could tonight,” Lee said. “But even with the other ones, too, we've lost some extremely key players and we continue just to push through. There’s a reason why it’s so tough to get in (to the Stanley Cup Playoffs). Things like this happen and adversity happens, and it's almost a little bit of a war of attrition in a way. And right now, we're plugging the holes.”
NOTES: Lee has scored 297 career goals, passing Brock Nelson (295) for fifth in Islanders history. ... Holmstrom has scored in consecutive games after ending a 17-game goal drought in a 5-4 shootout win against the Vegas Golden Knights on Tuesday.