Colorado went 12-6-2 in its next 20 games. MacKinnon had 34 points (10 goals, 24 assists) in that stretch.
Then the whopper came Jan. 24, when the Avalanche traded MacKinnon's longtime linemate and close friend Mikko Rantanen to the Carolina Hurricanes in a three-team deal involving the Chicago Blackhawks. Rantanen was their second leading scorer at the time with 64 points, including a team-high 25 goals.
Colorado got Martin Necas as part of the return. No offense to Necas, but at the time that seemed like a consolation prize considering how much Rantanen meant to MacKinnon and the team.
"It shocks the dressing room, I think," MacKinnon said two days later, following a two-assist game in a 5-4 win against the New York Rangers at Madison Square Garden. "It's sad, it [stinks] and it's just different."
It did not, however, mean worse for the Avalanche or MacKinnon.
They went 21-10-2 in their last 33 games after the trade and MacKinnon, playing the first 30 of those games, led them with 41 points (13 goals, 28 assists) while helping Necas make the adjustment. Necas had 28 points (11 goals, 17 assists) in 30 games for Colorado.
The Avalanche finished third in the Central Division with 49 wins and 102 points.
"He's my Hart guy," NHL Network's Mike Rupp, a retired NHL forward, told NHL.com. "There has been a lot of change and adversity, and he has dominated wire to wire, no matter who is there and who isn't."
Voting totals (points awarded on a 5-4-3-2-1- basis): Nathan MacKinnon, Avalanche, 66 points (six first-place votes); Nikita Kucherov, Lightning, 48 (four first-place votes); Connor Hellebuyck, Jets, 47 (three first-place votes); Leon Draisaitl, Edmonton Oilers, 41 (two first-place votes); Jack Eichel, Vegas Golden Knights, 15; Alex Ovechkin, Washington Capitals, 7 (one first-place vote); Mitch Marner, Toronto Maple Leafs, 6; Zach Werenski, Columbus Blue Jackets, 4; Cale Makar, Avalanche, 3; Nick Suzuki, Montreal Canadiens, 1; David Pastrnak, Boston Bruins, 1; Quinn Hughes, Vancouver Canucks, 1